3 European Projects Found
Searched on 125080 European Projects
FINISHED
Exploiting the power of human induced pluripotent stem cells to generate synthetic retinae in vitro for cell based therapies, drug discovery and disease modelling (RET-iPSC)
Start date: Jun 1, 2014, End date: May 31, 2018,
Blindness represents an increasing global problem with social and economic impacts both for the patients and society in general. Recent estimates indicate that the overall number of people with visual loss is 285 million globally, of whom 39 million are blind. In Europe, approximately 1 in 30 individuals experience sight loss and 75% of those are unemployed, a social burden which is anticipated t ...
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1
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FINISHED
Using evolution to uncover the importance of alternative pre mRNA splicing (ConserveAS)
Start date: Nov 1, 2013, End date: Oct 31, 2017,
A major mystery of the genome age is why complex and simple organisms all have a similar number of genes. My specialism is in ‘Alternative Splicing’ which is the means by which different products can be made from a single gene by differential incorporation of regions of pre-mRNA. Alternative splicing is therefore a mechanism to increase gene complexity in complex organisms like man and in complex ...
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1
Partner Participant
FINISHED
Assembly and coordination of peptidoglycan synthesis complexes during bacterial growth and cell division (PGRECONST)
Start date: Apr 1, 2014, End date: Mar 31, 2016,
In this project, I will investigate the proteins involved, and their interactions, in the formation of both peptidoglycan (PG) synthesis core complexes (elongasome and septosome) in the model bacterium Escherichia coli to gain new molecular insights into how the cell grows its cell wall during the cell cycle. This will be achieved by: (i) in vivo characterization of new or already known important ...
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