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B cells, splenic marginal zone, and complement -as opsonin and inflammatory mediator- in the immunopathogenesis of virally induced Type 1 Diabetes (CODIA)
Start date: Sep 1, 2007, End date: Aug 31, 2009,
Approximately 150 million people are affected with diabetes mellitus worldwide. One form of diabetes, Type I diabetes, is an autoimmune disease that accounts for about 10% of all cases. It is mediated by T cells of the immune system that turn against the host (autoreactivity), and specifically destruct insulin-producing beta-cells of the pancreas. The resulting lack of insulin leads to chronic ele ...
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