8 European Projects Found
Searched on 125080 European Projects
FINISHED
Intelligent Assessment of Pharmaceutical in the Environment (IPIE)
Start date: Jan 1, 2015, End date: Dec 31, 2018,
Active pharmaceutical ingredients (APIs) can be released to the natural environment during the manufacturing process, following use by patients or when unused medicines are disposed of. As APIs are biologically active compounds concerns have been raised about the potential effects of APIs in the environment on human and environmental health. Over the past 15 years, a substantial amount of work has ...
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29
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Oral biopharmaceutics tools (ORBITO)
Start date: Oct 1, 2012, End date: Sep 30, 2017,
The OrBiTo project will deliver novel methods and a framework for rational application of predictive biopharmaceutics tools for oral drug delivery. This will be achieved through novel propsective studies to define new methodlogies which will be validated using historical datasets from EFPIA partners. A combination of high quality in vitro or in silico characterizations of API and formulations will ...
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28
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BeTheCuRE (BTCURE)
Start date: Apr 1, 2011, End date: Mar 31, 2017,
BTCure is based on the recognition that RA is a heterogeneous disease where a major subset involves adaptive immunity, and that animal models have to develop the line with the different subsets of the human diseases in order to be optimally used for drug discovery and drug evaluation. Our aim is to develop an understanding of the early process in human arthritis subsets and the animal models that ...
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41
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European Patients' Academy on Therapeutic Innovation (EUPATI)
Start date: Feb 1, 2012, End date: Jan 31, 2017,
"The proposed project ""European Patients' Academy on Therapeutic Innovation"" (EUPATI) contributes to IMI’s goal of raising patients’ awareness and participation in pharmaceutical R&D. This patient-led academy will provide scientifically reliable, objective, comprehensive information to patients on pharmaceutical R&D. It will increase the capacity of well-informed patients to be effective advocat ...
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33
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Mechanism-Based Integrated Systems for the Prediction of Drug-Induced Liver Injury (MIP-DILI)
Start date: Feb 1, 2012, End date: Jan 31, 2017,
The current test systems employed by Industry are poorly predictive for Drug induced liver injury (DILI). The ‘MIP-DILI’ project will address this situation by the development of innovative preclinical test systems which are both mechanism-based and of physiological, pharmacological and pathological relevance to DILI in humans. An iterative, tiered approach with respect to test compounds, test sys ...
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29
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Incorporating real-life clinical data into drug development (GETREAL)
Start date: Oct 1, 2013, End date: Dec 31, 2016,
When a new medicine reaches the market, it is accompanied by an extensive data package that provides information about the safety and efficacy of the medicine in a clinical trial setting. However, assessing the expected future value of the medicines when used in “real world” clinical practice requires additional information next to traditional (pre-authorisation) clinical trials. Regulatory, HTA ...
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32
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Glycomics by High-throughput Integrated Technologies (GlycoHIT)
Start date: Jan 1, 2011, End date: Jun 30, 2014,
Protein glycosylation is a post-translational phenomenon that is involved in most physiological and disease processes including cancer. Most of the known cancer-associated glycobiomarkers were discovered individually using liquid chromatography and mass spectroscopy. Though valuable, there is room for improvement in these approaches for the discovery phase. There is also a critical need for innova ...
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16
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European Consortium in Healthcare Outcomes and cost-benefit research (ECHOUTCOME)
Start date: Feb 1, 2010, End date: Jan 31, 2013,
"ECHOUTCOME is an interdisciplinary European research platform with the aim of assessing methodological properties of Healthcare Outcome and Cost-Benefit studies. The ECHOUTCOME consortium is composed by eight partners from 4 countries including three academic international experts in Outcome Research from, the French Scientific Society in Health Economics, the European office of one Multinational ...
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