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Folate-Target Nanodevices To Activated Macrophages For Rheumatoid Arthritis (FOLSMART)
Start date: Jan 1, 2016, End date: Dec 31, 2019,
FOLSMART will bring to phase I clinical trials novel folate-based nanodevices (FBN) for the treatment of rheumatoid arthritis (RA). These nanodevices for folic acid (FA)-mediated targeting of activated macrophages showed improved clinical scores in a mouse model of RA when compared to methotrexate (MTX), a first-line drug therapy for the treatment of RA. In this way, FBN will be benchmarked agains ...
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