3 European Projects Found
Searched on 125080 European Projects
FINISHED
Function and computation in three-layer cortex (CORTEX SIMPLEX)
Start date: Feb 1, 2013, End date: Jan 31, 2018,
"Understanding brain function is one of the outstanding challenges of modern biology. Many studies focus on mammalian neocortex, a modular and versatile structure that operates equally well with different sensory inputs and for perception, planning as well as action. Neocortex, however, is remarkably complex. It contains many cell types, six layers, networks with local and long-range connections, ...
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1
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FINISHED
Dynamics of local transcriptomes and proteomes in neurons (Neuronal dynamics)
Start date: Jan 1, 2012, End date: Dec 31, 2016,
The ability of the nervous system to respond adaptively relies on modifications to existing proteins as well as changes in gene transcription and protein translation. An individual neuron in the brain possesses approximately 10.000 synapses, many of which are hundreds of microns away from the cell body. As many of the changes to environmental stimuli occur at synapses, the question arises as to ho ...
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1
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FINISHED
Local Processing of Dendritically Synthesized Membrane Proteins (DENDRITIC PROCESSING)
Start date: Apr 1, 2012, End date: Mar 31, 2015,
"The local synthesis and degradation of proteins represent a particularly efficient means to adaptively modify the composition of targeted dendritic branches and associated synapses.Recent data from our laboratory show that numerous mRNA encoding neurotransmitter receptors and voltage-gated channels are enriched in distal dendrites, indicating that local translation sustains local membrane protein ...
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