Search for European Projects

8 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Macroencapsulated Porcine Pancreatic Islets to cure Diabetes Mellitus type 1/2 (XENOISLET)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

During the last five years, within the EU FP6 Integrated Project XENOME (LSHB-CT-2006-037377), we have convincingly demonstrated in primates that a complete control of induced type 1 diabetes is routinely obtained for 6/8 months after transplantation of subcutaneous alginate macroencapsulated porcine islets xenograft without the use of any immunosuppression. In order to improve the function of pig ...
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 5

 FINISHED 

EpiHealthNet

Start date: May 1, 2013, End date: Apr 30, 2017,

Scientific evidence clearly indicates that ageing and health in adult life is programmed by genetic and epigenetic mechanisms early in life.Developmental plasticity in response to the environment, including nutrient availability, of mammalian embryos indicates the capacity fornewly emerging embryonic and extraembryonic cell lineages to initiate compensatory responses which may attune nutrient deli ...
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 9

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Linking perturbed maternal environment during periconceptional development, due to diabetes, obesity or assisted reproductive technologies, and altered health during ageing (EpiHealth)

Start date: Nov 1, 2011, End date: Oct 31, 2015,

Scientific evidence clearly indicates that ageing and health in adult life is programmed by genetic and epigenetic mechanisms early in life. Developmental plasticity in response to the environment, including nutrient availability, of mammalian embryos indicates the capacity for newly emerging embryonic and extraembryonic cell lineages to initiate compensatory responses which may attune nutrient de ...
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 7

 FINISHED 

High resolution tools to understand the functional role of protein intrinsic disorder (IDPBYNMR)

Start date: Nov 1, 2010, End date: Oct 31, 2014,

Recent evidence shows that a large share of proteins gain functional advantages by remaining natively unstructured, either completely or partially, thus challenging well-established concepts in structural biology. In order to characterize the highly dynamical nature of such “intrinsically disordered proteins”, and follow their (possible) reorganization by interacting with partners, new integrated ...
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 10

 FINISHED 

A IAPP on the Role of NCAM in Stem Cell Differentiation (STEMCAM)

Start date: Sep 1, 2010, End date: Aug 31, 2014,

The STEMCAM project is a 4-years training and transfer of knowledge program between two distinguished academic groups in stem cell research, two highly innovative SMEs and a company leader in development of media for stem cell research, to foster long-term industry-academy collaboration and partnership in the field of stem cells research and applications. The scientific and industrial aim of STEMC ...
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 6

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Improved gene transfer system to iPS cells in mouse (InduVir)

Start date: Oct 1, 2009, End date: Sep 30, 2013,

The scientific aim of InduVir is to produce novel comparative information on the generation, maintenance and characteristics of iPS cells in mouse and on their differentiation towards different, especially cardiac lineages. In InduVir we are aiming to develop a novel system, by using removable transposons and polycistronic, deletable lentiviruses and therefore significantly reduce the risk of mali ...
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 1

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Comparative Analysis of Rabbit and Mouse Pluripotency in Embryos and Stem Cells (RabPStem)

Start date: Sep 1, 2010, End date: Aug 31, 2013,

The RabPStem proposal is aimed at increasing the fundamental knowledge of basic biological processes of cell pluripotency and differentiation by generating new comparative data on gene expression associated with cell pluripotency. RabPStem links for the first time research activities in a non-rodent (rabbit) and rodent (mouse) mammalian systems and in different cell types, from pluripotent cells i ...
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 1

 FINISHED 

Induced pluripotent stem cells for cardiomyocyte generation in mouse (InduHeart)

Start date: Mar 16, 2009, End date: Mar 15, 2013,

The scientific aim of InduHeart is to produce novel comparative information on the generation, maintenance, characteristics of iPS cells in mouse and on their differentiation towards the cardiac lineage. InduHeart will also employ mouse embryonic stem (ES) cell lines to develop innovative methods for the targeted preparation of differentiated cardiac muscle cells. The characteristics of cardiomyoc ...
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 1