Archive of European Projects

28 European Projects Found

Searched on 125080 European Projects

 FINISHED 
EURenOmics will integrate several established consortia devoted to rare kidney diseases with eminent need and potential for diagnostic and therapeutic progress (i.e. steroid resistant nephrotic syndrome, membranous nephropathy, tubulopathies, complement disorders such a haemolytic uraemic syndrome, and congenital kidney malformations). The Consortium has access to the largest clinical cohorts asse ...
Read Project

 29

 FINISHED 
"The number of road traffic accident fatalities world wide has recently reached 1.3 million each year, with between 20 and 50 million injuries being caused by road accidents. In theory, all accidents can be avoided. Studies showed that more than 90% road accidents are caused by or related to human error. Developing an efficient system that can detect hazardous situations robustly is the key to red ...
Read Project

 3

 FINISHED 
Diagnostic radiation represents an indispensable, sometimes life-saving, tool in modern medicine. However, the growing use of computerized tomography (CT) is a topic of concern in radiological protection, especially for children and adolescents. Children are generally more sensitive to the carcinogenic effects of ionizing radiation than adults. In addition, they have a longer life-span to express ...
Read Project

 22

 FINISHED 
Over the last 40 years, treatment for childhood and adolescent cancer has improved greatly; 5- year survival after childhood cancer is now 80% in developed countries. Approximately 1 individual in 750 of young adults is now a childhood cancer survivor. Epidemiologic data on the number of European childhood cancer long-term survivors are not available, but estimates suggest a number between 300,000 ...
Read Project

 18

 FINISHED 

Mitochondrial European Educational Training (MEET)

Start date: 14 Jan 2013, End date: 13 Jan 2017,

"The expanding diversification and specialization of knowledge and the growing complexity of contemporary research in translational research warrant the creation of cooperative multi-disciplinary networks including both basic and medically oriented expertise. This notion is especially true for Mitochondrial Medicine which aims at understanding the physiopathological mechanisms sharing the features ...
Read Project

 10

 FINISHED 

Advanced Multidisciplinary Training in Molecular Bacteriology (AMBER)

Start date: 01 Jan 2013, End date: 31 Dec 2016,

"The advancement in life sciences has created a growing number of disciplines that are required to elucidate the increasingly complicated biological questions. This has led to an unsurpassed level of knowledge, but it has also resulted in a continuous specialization in PhD trainings, which makes the students less prepared for complex present day biological questions. To provide a better comprehens ...
Read Project

 9

 FINISHED 
RARE-Bestpractices will develop a sustainable networking platform, supporting the collection of standardized and validated data and efficient exchange of knowledge and reliable information on rare diseases (RD).RD are characterized by low prevalence (EU – 5:10000 persons). There are more than 5000, overall affecting about 30 million citizens of all ages in the EU. RD are often life-threatening and ...
Read Project

 16

 FINISHED 
Ageing is an inexorable homeostatic failure of largely unknown aetiology that leads to increased vulnerability to disease limiting the quality of life in the elderly and creating high costs to the society. Until recently, the daunting complexity of the ageing process, the conspicuous lack of tools to study it, and a dearth of experimentally tractable model systems have greatly hindered any hypothe ...
Read Project

 9

 FINISHED 

Retina-inspired ENcoding for advanced VISION tasks (RENVISION)

Start date: 01 Mar 2013, End date: 31 Aug 2016,

The retina is a sophisticated distributed processing unit of the central nervous system encoding visual stimuli in a highly parallel, adaptive and computationally efficient way. Recent studies show that rather than being a simple spatiotemporal filter that encodes visual information, the retina performs sophisticated non-linear computations extracting specific spatio-temporal stimulus features in ...
Read Project

 4

 FINISHED 
Duchenne muscular dystrophy (DMD) is a progressive, lethal muscle degenerative condition arising from the absence of dystrophin in skeletal and cardiac muscles. 65% of DMD boys have out-of-frame deletions. Modulation of pre-mRNA splicing by exon skipping is the most promising molecular intervention in DMD. 2 Phase Ib and 2 Phase IIa clinical trials (MDEX Consortium in collaboration with Sarepta Th ...
Read Project

 10

 FINISHED 

Mucus Permeating Nanoparticulate Drug Delivery Systems (ALEXANDER)

Start date: 01 Apr 2012, End date: 31 Mar 2016,

The objective of the ALEXANDER project is the identification of novel strategies (e.g., proteolytic enzyme strategy, thiomer strategy, zeta potential changing systems, SNEDDS strategy) and the optimization of existing strategies (e.g., disulfide breaking strategy and slippery surface strategy) for the efficient transport of nanocarriers through the mucus gel layer (e.g., intestinal, nasal, ocular, ...
Read Project

 20

 FINISHED 
"MICROGENNET is a collaboration of 16 distinguished universities and research institutes worldwide. The overall aim of the exchange programme is to build, extend and strengthen sustainable collaborations between the partners so as to create a community driven knowledge base for micronutrient genomics research. Currently, the data on nutrient effects on health are scattered in publications and da ...
Read Project

 9

 FINISHED 
Recent pharmacovigilance (PV) issues have led to questions regarding the ability of the current PV system to meet the global needs. Controversies around the assessment of spontaneous reports and conflicting results from pharmacoepidemiology studies may lead to delay in, or inappropriate, regulatory decisions. The PROTECT consortium, consisting of 20 core partners lead by the European Medicines Age ...
Read Project

 36

 FINISHED 
The present proposal sees the development of business and value creation models as central to the development of personalised nutrition and thus it is intended to engage in a series of interviews with key stakeholders, which will generate a number of scenarios to be considered by these stakeholders. Parallel to that we will run some focus groups with consumers and develop a tool to ascertain consu ...
Read Project

 28

 FINISHED 

Tailored implementation for chronic diseases (TICD)

Start date: 01 Feb 2011, End date: 28 Feb 2015,

Project aim. Chronic diseases represent an important challenge facing healthcare systems. Research has consistently shown gaps between knowledge and practice for chronic illness care. Tailoring implementation interventions implies that the choice and content of implementation interventions are based on assessment of local barriers and enabling factors. It is widely believed that tailoring contribu ...
Read Project

 7

 FINISHED 
Symbiosis research is currently in the midst of a revolution as molecular techniques are leading to major breakthroughs in our understanding of interactions between animals and microbes. There is an emerging recognition that all animals are intimately associated with a complex community of beneficial microbes that are essential for their development, nutrition, and health. Thus, modern symbiosis r ...
Read Project

 10

 FINISHED 

Optimizing delivery of health care interventions (ODHIN)

Start date: 01 Jan 2011, End date: 31 Dec 2014,

ODHIN is a Europe wide project involving research institutions from nine European countries that will help to optimize the delivery of health care interventions by understanding how better to translate the results of clinical research into every day practice. ODHIN will use the implementation of identification and brief intervention (IBI) programmes for hazardous and harmful alcohol consumption (H ...
Read Project

 21

 FINISHED 
Delayed graft function (DGF) is defined as the need for dialysis within seven days of renal transplantation (DGF promotes allograft rejection, requires prolonged dialysis and hospitalisation, and increases the likelihood of graft failure and ultimately the duration of renal graft survival-expectancy. The incidence of DGF occurs in 21-44% of cases following cadaveric renal graft. Several rare dise ...
Read Project

 10

 FINISHED 

Pharmaceutical Medicine Training Programme (PHARMATRAIN)

Start date: 01 May 2009, End date: 30 Apr 2014,

"The proposed Pharmaceutical Medicine Training Programme provides a comprehensive solution for the complex needs of integrated drug development for all professionals involved, incl. physicians, pharmaceutical scientists,biologists, biometricians, health economists, and safety and regulatory scientists from universities, regulatory agencies, large, middle-sized and small pharmaceutical enterprises, ...
Read Project

 52

 FINISHED 

The evolution of gene content in parasitic protozoa (EVOGCPROTO)

Start date: 01 Apr 2012, End date: 31 Mar 2014,

"Protozoan parasites from diverse evolutionary lineages including Trypanosoma and Leishmania, Giardia, Entamoeba, Plasmodium and the microsporidia have a major impact on human health, especially in developing countries and among immunocompromised individuals. During their evolution as parasites these organisms can both lose pathways if they can steal host metabolites and gain genes that may help t ...
Read Project

 1

 FINISHED 

Genomic & Epigenomic Complex Disease Epidemiology (GEoCoDE)

Start date: 01 Mar 2010, End date: 28 Feb 2014,

Genetic and epigenetic epidemiology are rapidly developing aspects of population-based health research that have clear translational potential. These endeavours both benefit considerably from extensive international collaborations. Establishing robust associations between genetic variation and common complex disease phenotypes requires very large sample sizes than can only realistically be generat ...
Read Project

 9

 FINISHED 
"New and recent developments have revolutionized the prostate cancer research and clinical arenas, requiring the next generation scientists to have comprehensive knowledge and expertise in basic, clinical and applied research. PRO-NEST offers young researchers a European integrated, multi-disciplinary training programme to become an independent and all-round scientist and team leader in (prostate) ...
Read Project

 18

 FINISHED 
"The European Commission and other funding agencies make a large investment in child health research. The health of our children is satisfactory, but there are serious concerns, for example, obesity, mental health, alcohol abuse, and sexuality. We know that there are strong links between the health of young people and their social inclusion and level of education. Our objective is to establish a s ...
Read Project

 27

 FINISHED 

Fatty liver: Inhibition of Progression (FLIP)

Start date: 01 Jan 2010, End date: 30 Jun 2013,

"Non-alcoholic fatty liver disease (NAFLD) has become one of the top concerns for the practising hepatogastroenterologist due to the obesity epidemic and its potential to progress to advanced liver disease which significantly impacts on overall and liver-related mortality. The aim of the FLIP (Fatty Liver: Inhibition of Progression) project is to understand and prevent the progression of liver dis ...
Read Project

 17

 FINISHED 

Arrhythmogenic potential of drugs (ARITMO)

Start date: 01 Jan 2010, End date: 30 Jun 2013,

The ability of some compounds to prolong the QT interval of the electrocardiogram and to precipitate Torsade de Pointes (TdP, a potentially fatal arrhythmia) has caused several regulatory interventions, including drug withdrawals. Specific guidelines have been implemented to detect QT liability of new compounds as early as possible. However there is growing evidence that an increase in the QT inte ...
Read Project

 21

 FINISHED 
Advanced Therapy Medicinal Products (ATMPs) are medicinal products for human use, based on gene therapy, somatic cell therapy or tissue engineering. A rapidly growing area in translational research, they represent the ‘next generation’ of complex medicines for complex diseases and pose particular challenges to medicines regulation.Regulation (EC) No 1394/2007 has been designed to ensure the free m ...
Read Project

 9

 FINISHED 
"The main objective of the project will be to characterize the molecular cell biology of proliferation in cell-wall deficient (L-form) derivatives of Bacillus. subtilis. L-forms can apparently arise from a wide range of bacteria and are often found in clinical situations. Recent work in the Errington lab has provided a highly tractable model system for studying the L-form state. B. subtilis L-form ...
Read Project

 1

 FINISHED 
"The rapidly expanding knowledge of NMDs genetic diagnosis, pathogenesis and therapeutic possibilities has provided new targets for disease characterisation, early diagnosis, drug discovery and development as well as has raised many questions about how to translate this knowledge into clinical practice as (initial) clinical trials typically run for such a short time that clinical improvement can h ...
Read Project

 15